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NP G2 044

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Drug Profile

NP G2 044

Alternative Names: DC-05F-01; NP-G2-044

Latest Information Update: 13 Aug 2025

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At a glance

  • Originator Novita Pharmaceuticals; Weill Cornell Medical College
  • Developer CR Double-Crane Pharmaceuticals; Novita Pharmaceuticals
  • Class Amides; Antineoplastics; Fluorinated hydrocarbons; Furans; Indazoles; Small molecules
  • Mechanism of Action Fascin protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Ovarian cancer; Small cell lung cancer; Solid tumours

Most Recent Events

  • 07 Aug 2025 Novita Pharmaceuticals plans a phase II/III ULTIMUS-1 trial for Ovarian Cancer (Combination therapy, Second-line therapy or greater, Late-stage) (PO) in August 2025 (NCT07109414)
  • 30 May 2025 Updated efficacy and adverse events data from a phase I/II trial in Solid tumors presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 11 Sep 2024 Phase-I/II clinical trials in Ovarian cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT06873542)

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