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NP G2 044

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Drug Profile

NP G2 044

Alternative Names: DC-05F-01; NP-G2-044

Latest Information Update: 22 Jan 2026

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At a glance

  • Originator Novita Pharmaceuticals; Weill Cornell Medical College
  • Developer CR Double-Crane Pharmaceuticals; Novita Pharmaceuticals
  • Class Amides; Antineoplastics; Fluorinated hydrocarbons; Furans; Indazoles; Small molecules
  • Mechanism of Action Fascin protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Ovarian cancer
  • Phase I/II Small cell lung cancer; Solid tumours

Most Recent Events

  • 12 Jan 2026 NP G2 044 receives Orphan Drug status for Pancreatic cancer in USA
  • 24 Oct 2025 Phase-II/III clinical trials in Ovarian cancer (Combination therapy, Late-stage disease, Second-line therapy or greater) in USA (PO) (NCT07109414)
  • 24 Oct 2025 Phase-II/III clinical trials in Ovarian cancer (Late-stage disease, Second-line therapy or greater, Monotherapy) in USA (PO) (NCT07109414)

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