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UCART 123

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Drug Profile

UCART 123

Alternative Names: Anti-CD123 CAR-T Cells-Cellectis; UCART-123; UCART-123v1.2

Latest Information Update: 31 Mar 2025

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At a glance

  • Originator Cellectis
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Suspended Acute myeloid leukaemia; Blastic plasmacytoid dendritic cell neoplasm

Most Recent Events

  • 13 Mar 2025 Suspended - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in USA (IV)
  • 13 Mar 2025 Suspended - Phase-I for Blastic plasmacytoid dendritic cell neoplasm (First-line therapy) in USA (IV)
  • 13 Mar 2025 Suspended - Phase-I for Blastic plasmacytoid dendritic cell neoplasm (Second-line therapy or greater) in USA (IV)

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