HTI 1090

Drug Profile

HTI 1090

Alternative Names: HTI-1090; SHR 9146

Latest Information Update: 21 Nov 2017

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At a glance

  • Originator Atridia; Hengrui Therapeutics; Jiangsu Hengrui Medicine Co.
  • Developer Atridia
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Indoleamine-pyrrole 2,3-dioxygenase inhibitors; Tryptophan oxygenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 13 Apr 2018 Jiangsu HengRui Medicine plans a phase I trial of SHR 9146 in combination with SHR 1210 for Solid tumours (Combination therapy, Late-stage disease or greater) in May 2018 (NCT03491631)
  • 30 Aug 2017 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in Australia (PO) (NCT03208959)
  • 03 May 2017 The US FDA approves clinical registration application for HTI 1090 in Solid tumours in USA
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