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BioLexa - Hoth Therapeutics

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Drug Profile

BioLexa - Hoth Therapeutics

Alternative Names: BioLexa™; Gentamicin/Diethylenetriaminepentaacetic acid

Latest Information Update: 13 Aug 2025

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At a glance

  • Originator University of Cincinnati
  • Developer Hoth Therapeutics; University of Cincinnati
  • Class Antibacterials; Skin disorder therapies
  • Mechanism of Action Chelating agents; Protein 30S ribosomal subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Atopic dermatitis
  • No development reported Bacterial infections; Wounds

Most Recent Events

  • 13 Aug 2025 BioLexa is still in phase I development for Atopic Dermatitis
  • 28 Apr 2024 No recent reports of development identified for phase-I development in Atopic-dermatitis in Australia (Topical, Lotion)
  • 06 Sep 2023 Final efficacy data from a phase I trial in atopic dermatitis released by Hoth Therapeutics

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