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Golexanolone - Umecrine Cognition

Drug Profile

Golexanolone - Umecrine Cognition

Alternative Names: GR-3027

Latest Information Update: 02 Aug 2019

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At a glance

  • Originator Umecrine Cognition
  • Class Alkynes; Androstanes; Hepatoprotectants; Imines; Neuroprotectants; Small molecules
  • Mechanism of Action GABA-A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hypersomnia
  • Phase I/II Hepatic encephalopathy

Most Recent Events

  • 02 Aug 2019 Chemical structure information added
  • 12 Dec 2018 Umecrine Cognition has patent protection for golexanolone (GR 3027) for its use in hepatic encephalopathy in European Union
  • 19 Oct 2018 Umecrine Cognition completes a phase IIa trial in Hypersomnia in Finland, Denmark and Sweden (EudraCT2017-002127-16)
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