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Golexanolone - Umecrine Cognition

Drug Profile

Golexanolone - Umecrine Cognition

Alternative Names: GR-3027

Latest Information Update: 16 Mar 2021

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At a glance

  • Originator Umecrine Cognition
  • Class Alkynes; Androstanes; Hepatoprotectants; Imines; Neuroprotectants; Small molecules
  • Mechanism of Action GABA-A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Hepatic encephalopathy
  • No development reported Hypersomnia

Most Recent Events

  • 16 Mar 2021 Phase-I/II development in Hepatic encephalopathy is still ongoing in Denmark, Finland and Sweden (PO) (Umecrine Cognition's website, March 2021)
  • 16 Mar 2021 No development reported - Phase-II for Hypersomnia in Finland, Sweden and Denmark (PO) (Umecrine Cognition's website, March 2021)
  • 20 Jan 2020 Umecrine Cognition completes a phase I/II trial in Hepatic encephalopathy (In volunteers) in Finland, Sweden and Denmark (PO) (EudraCT2016-003651-30)
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