Lexanersen - WaVe Life Sciences
Alternative Names: BMTR-5149; Lexanersen sodium; WV-2603; WVE-120102Latest Information Update: 28 Mar 2024
At a glance
- Originator WaVe life Sciences
- Class Antisense oligonucleotides; Neuroprotectants
- Mechanism of Action RNA interference
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Huntington's disease
Most Recent Events
- 31 Jul 2023 Wave Life Sciences terminates its collaboration with Takeda with respect to C9 Target and ATXN3 Target
- 16 Jun 2021 Wave Life Sciences terminates a phase I/II trial in Huntington's disease in Australia, Canada, Denmark, France, Germany Poland and the UK (Intrathecal) due to lack of efficacy (NCT04617860)
- 10 May 2021 WaVe life Sciences terminates a phase Ib/IIa trial in Huntington's disease in USA, Australia, Canada, Denmark, France, Germany, Poland and United Kingdom (Intrathecal, Injection) (NCT03225846) (EudraCT2016-005142-39)