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Lexanersen - WaVe Life Sciences

Drug Profile

Lexanersen - WaVe Life Sciences

Alternative Names: BMTR-5149; Lexanersen sodium; WV-2603; WVE-120102

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator WaVe life Sciences
  • Class Antisense oligonucleotides; Neuroprotectants
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Huntington's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Huntington's disease

Most Recent Events

  • 16 Jun 2021 Wave Life Sciences terminates a phase I/II trial in Huntington's disease in Australia, Canada, Denmark, France, Germany Poland and the UK (Intrathecal) due to lack of efficacy (NCT04617860)
  • 10 May 2021 WaVe life Sciences terminates a phase Ib/IIa trial in Huntington's disease in USA, Australia, Canada, Denmark, France, Germany, Poland and United Kingdom (Intrathecal, Injection) (NCT03225846) (EudraCT2016-005142-39)
  • 06 Apr 2021 Asuragen has been acquired by Bio-Techne
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