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Bemnifosbuvir - Atea Pharmaceuticals

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Drug Profile

Bemnifosbuvir - Atea Pharmaceuticals

Alternative Names: AT-511-hemisulfate salt; AT-527 free base; AT‐527; RG-6422; RO 7496998

Latest Information Update: 09 Aug 2024

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At a glance

  • Originator Atea Pharmaceuticals
  • Class Amines; Antivirals; Esters; Fluorinated hydrocarbons; Phosphorus compounds; Purine nucleotides; Small molecules
  • Mechanism of Action DNA-directed RNA polymerase inhibitors; Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III COVID 2019 infections
  • Phase II Hepatitis C

Most Recent Events

  • 30 Jun 2024 Atea Pharmaceuticals completes enrolment in its phase II trial in Hepatitis C (Combination therapy) in USA, Brazil, Canada, India, South Korea, Mauritius, Moldova, Pakistan, Philippines, Romania, South Africa and Turkey (PO) (NCT05904470)
  • 15 Jun 2024 Atea Pharmaceuticals completes a phase I pharmacokinetic and safety trial in patients with various degrees of renal insufficiency in Canada (PO) (NCT05618314)
  • 05 Jun 2024 Adverse events data from the phase II trial in Hepatitis C presented at the European Association for the Study of the Liver Congress (EASL-2024)

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