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Bemnifosbuvir - Atea Pharmaceuticals

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Drug Profile

Bemnifosbuvir - Atea Pharmaceuticals

Alternative Names: AT-511-hemisulfate salt; AT-527 free base; AT‐527; RG-6422; RO 7496998

Latest Information Update: 15 May 2025

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At a glance

  • Originator Atea Pharmaceuticals
  • Class Amines; Antivirals; Esters; Fluorinated hydrocarbons; Phosphorus compounds; Purine nucleotides; Small molecules
  • Mechanism of Action DNA-directed RNA polymerase inhibitors; Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III COVID 2019 infections
  • Phase II Hepatitis C

Most Recent Events

  • 07 May 2025 Efficacy data from a phase II trial in Hepatitis C released by Atea
  • 15 Nov 2024 Efficacy data from a phase I trial in healthy volunteers presented at the 75th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2024)
  • 15 Nov 2024 Efficacy data from a phase II trial in Hepatitis C infection presented at the Liver Meeting 2024 75th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2024)

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