Drug Profile

M 6495

Alternative Names: ALX 1141; Anti-ADAMTS5 Nanobody^®; M 6495

Latest Information Update: 28 Jan 2023

Price :

$50 ^*

Note:

Adis is an information provider. We do not sell or distribute actual drugs.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

Originator Ablynx; Merck KGaA
Developer Merck KGaA
Class Anti-inflammatories; Antirheumatics; Proteins; Single-domain antibodies
Mechanism of Action ADAMTS5 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

No development reported Osteoarthritis

Most Recent Events

28 Jan 2023 No recent reports of development identified for phase-I development in Osteoarthritis in Denmark (SC)
04 Jan 2021 M 6495 is still in phase I trials for Osteoarthritis in Denmark (Merck Serono pipeline, December 2020)
28 Dec 2020 No recent reports of development identified for phase-I development in Osteoarthritis in Unknown (Parenteral)

You need to be a logged in or subscribed to view this content Request demo

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com