Drug Profile
Eflornithine oral - Panbela Therapeutics
Alternative Names: CPP-1X; CPP-1X-S; CPP-1X-T; DFMO; Difluoromethylornithine; Difluoromethylornithine (DFMO); IWILFINLatest Information Update: 28 Feb 2024
Price :
$50
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At a glance
- Originator Cancer Prevention Pharmaceuticals
- Developer Atrium Health; Children's Oncology Group; Indiana University; KC Pharmaceuticals; National Cancer Institute (USA); New Approaches to Neuroblastoma Therapy Consortium; Panbela Therapeutics; Vanderbilt University Medical Center
- Class Antihyperglycaemics; Antineoplastics; Basic amino acids; Diamino amino acids; Small molecules
- Mechanism of Action Ornithine decarboxylase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Registered Neuroblastoma
- Phase II Colorectal cancer; Gastric cancer; Prostate cancer; Type 1 diabetes mellitus
- Phase I Non-small cell lung cancer
- Preclinical Cancer; Multiple myeloma
Most Recent Events
- 28 Feb 2024 No recent reports of development identified for phase-I development in Neuroblastoma(Combination therapy, In adolescents, In children, Second-line therapy or greater, In adults) in Australia (PO)
- 28 Feb 2024 No recent reports of development identified for phase-I development in Neuroblastoma(Combination therapy, In adolescents, In children, Second-line therapy or greater, In adults) in Canada (PO)
- 28 Feb 2024 No recent reports of development identified for phase-I development in Neuroblastoma(Combination therapy, In adolescents, In children, Second-line therapy or greater, In adults) in USA (PO)