Eflornithine oral - Panbela Therapeutics
Alternative Names: CPP-1X; CPP-1X-S; CPP-1X-T; D,L-ɑdifluoromethylornithine; DFMO; Difluoromethylornithine; Difluoromethylornithine (DFMO); IFINWIL; IWILFINLatest Information Update: 10 Jul 2025
At a glance
- Originator Cancer Prevention Pharmaceuticals
- Developer Atrium Health; Children's Oncology Group; Indiana University; KC Pharmaceuticals; National Cancer Institute (USA); New Approaches to Neuroblastoma Therapy Consortium; Norgine; Panbela Therapeutics; US WorldMeds; Vanderbilt University Medical Center
- Class Antihyperglycaemics; Antineoplastics; Basic amino acids; Diamino amino acids; Small molecules
- Mechanism of Action Ornithine decarboxylase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Marketed Neuroblastoma
- Phase II Colorectal cancer; Gastric cancer; Prostate cancer; Type 1 diabetes mellitus
- Phase I/II Non-small cell lung cancer
- Preclinical Cancer; Multiple myeloma