Pirtobrutinib - Loxo Oncology
Alternative Names: Jaypirca; LOXO-305; LY 3527727; RXC-005Latest Information Update: 20 Dec 2024
Price :
$50 *
At a glance
- Originator Redx Pharma
- Developer Eli Lilly and Company; Loxo Oncology
- Class Amides; Amines; Antineoplastics; Fluorobenzenes; Pyrazoles; Small molecules
- Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Chronic lymphocytic leukaemia; Mantle-cell lymphoma
- Phase II Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
- Phase I/II Marginal zone B-cell lymphoma
- No development reported Haematological malignancies
Most Recent Events
- 18 Dec 2024 Updated efficacy data from the phase III BRUIN CLL-321 trial in Chronic lymphocytic leukemia released by Eli Lilly and Company
- 15 Dec 2024 pirtobrutinib licensed to Innovent Biologics in China
- 09 Dec 2024 The efficacy and adverse event data from a phase III trial in Chronic lymphocytic leukaemia released by Eli Lilly and Company