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AP 325

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Drug Profile

AP 325

Alternative Names: AP-325

Latest Information Update: 05 Jun 2023

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At a glance

  • Originator Algiax Pharmaceuticals
  • Class Amides; Analgesics; Antihyperglycaemics; Imidazoles; Nitriles; Pyridines; Pyridones; Small molecules; Triazines
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors; GABA A receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinal cord injuries
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Neuropathic pain
  • Discontinued Spinal cord injuries

Most Recent Events

  • 30 May 2023 Adverse events data from the phase II CURE trial in Neuropathic pain released by Algiax Pharmaceuticals
  • 28 Sep 2022 AP 325 is still in phase-II clinical trials for Neuropathic pain in Czech Republic, Spain and Germany (PO) (EudraCT-2019-003502-28) (NCT04429919)
  • 16 Dec 2021 Angiax Pharmaceuticals plans a phase II trial for Type2 diabetes (Treatment-naive) in Germany (NCT05160272)

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