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Runcaciguat modified release - Bayer

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Drug Profile

Runcaciguat modified release - Bayer

Alternative Names: BAY 1101042; sGC Activator 1

Latest Information Update: 08 Jul 2024

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At a glance

  • Originator Bayer
  • Class Amines; Chlorobenzenes; Cyclopropanes; Fluorinated hydrocarbons; Propionic acids; Small molecules; Urologics
  • Mechanism of Action Guanylate cyclase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diabetic retinopathy; Renal failure

Most Recent Events

  • 22 Apr 2024 Bayer completes the phase II trial in Diabetic retinopathy in Germany, Poland, Portugal, US, Bulgaria, Latvia, Netherlands, Romania, Slovakia, Spain, Switzerland, UK (PO) (EudraCT2020-002333-15) (NCT04722991)
  • 29 Apr 2022 Bayer completes the CONCORD phase II trial in Renal failure in Germany, Israel, Slovakia, Ukraine, Sweden, Poland, Italy, Finland, Bulgaria, Spain, Belgium, Austria, Denmark (PO) (NCT04507061)
  • 13 Jul 2021 Bayer prematurely terminates its phase I trial in Renal failure (In Volunteers) in Germany (PO, Tablet) due to changes in the company's development strategy(NCT04820621) (EudraCT2020-005716-22)

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