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Zimberelimab - Arcus Biosciences/Guangzhou Gloria Biosciences/Taiho Pharmaceutical

Drug Profile

Zimberelimab - Arcus Biosciences/Guangzhou Gloria Biosciences/Taiho Pharmaceutical

Alternative Names: AB 122; GLS 010; GS-0122; WBP 3055; YUTUO

Latest Information Update: 09 Jun 2024

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At a glance

  • Originator WuXi Biologics
  • Developer Arcus Biosciences; Gilead Sciences; Guangzhou Gloria Biosciences; Memorial Sloan-Kettering Cancer Center; Strata Oncology; Taiho Pharmaceutical; UCLAs Jonsson Comprehensive Cancer Center; University of Texas Southwestern Medical Center; Yale University
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cervical cancer; Hodgkin's disease
  • Phase III Gastrointestinal cancer; Non-small cell lung cancer
  • Phase II Biliary cancer; Liposarcoma; Liver cancer; Malignant melanoma; Rectal cancer
  • Phase I/II Colorectal cancer; Pancreatic cancer; Solid tumours
  • No development reported Cancer; Glioblastoma
  • Discontinued Prostate cancer

Most Recent Events

  • 02 Jun 2024 Efficacy and adverse events data from the phase Ib/II ARC-9 trial in Colorectal cancer released by Gilead Sciences
  • 01 Jun 2024 Efficacy and adverse events data from the phase II EDGE-Gastric trial in Gastrointestinal cancer released by Gilead Sciences and Arcus Biosciences
  • 28 May 2024 No recent reports of development identified for phase-I development in Glioblastoma(Combination therapy, Recurrent, Second-line therapy or greater) in USA (IV)
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