Drug Profile

MRM 3379

Alternative Names: DNS-3379; ENT-3379; MRM-3379

Latest Information Update: 04 Mar 2026

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At a glance

Originator Dart NeuroScience; Enthorin Therapeutics
Developer Dart NeuroScience; Mirum Pharmaceuticals
Class
Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Fragile X syndrome
Discontinued Ischaemic stroke

Most Recent Events

25 Feb 2026 MRM 3379 receives Fast Track designation for Fragile X syndrome [PO,Capsule] (In adolescents, In adults) in USA
24 Oct 2025 Phase-II clinical trials in Fragile X syndrome (In adolescents, In adults) in USA (PO) (NCT07209462)
21 Mar 2025 Mirum Pharmaceuticals in-licenses MRM 3379 from Dart Neuroscience

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