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MRM 3379

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Drug Profile

MRM 3379

Alternative Names: DNS-3379; ENT-3379; MRM-3379

Latest Information Update: 08 Nov 2025

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At a glance

  • Originator Dart NeuroScience; Enthorin Therapeutics
  • Developer Dart NeuroScience; Mirum Pharmaceuticals
  • Class
  • Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Fragile X syndrome
  • Discontinued Ischaemic stroke

Most Recent Events

  • 24 Oct 2025 Phase-II clinical trials in Fragile X syndrome (In adolescents, In adults) in USA (PO) (NCT07209462)
  • 21 Mar 2025 Mirum Pharmaceuticals in-licenses MRM 3379 from Dart Neuroscience
  • 20 Mar 2025 Discontinued - Phase-II for Ischaemic stroke in Australia (unspecified route)

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