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H3B 6545

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Drug Profile

H3B 6545

Alternative Names: H3B-6545

Latest Information Update: 13 Jul 2024

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At a glance

  • Originator H3 Biomedicine
  • Developer Eisai Co Ltd; H3 Biomedicine
  • Class Amides; Amines; Antineoplastics; Fluorocarbons; Indazoles; Pyridines; Small molecules
  • Mechanism of Action Estrogen receptor alpha antagonist
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HER2 negative breast cancer

Most Recent Events

  • 31 May 2024 Updated adverse events and efficacy data from a phase I/II trial in Breast cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 31 May 2024 Efficacy and adverse events data from a phase Ib trial in Breast cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 26 Oct 2023 Eisai completes a phase I/II trial for Her2 negative Breast cancer (Metastatic disease, Late-stage disease, Second-line therapy or greater) in France (PO) (NCT03250676)

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