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KA 2507

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Drug Profile

KA 2507

Alternative Names: HDAC6 inhibitor - Karus Therapeutics; HDAC6i - Karus Therapeutics; KA-2507

Latest Information Update: 28 Sep 2022

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At a glance

  • Originator Karus Therapeutics
  • Developer Karus Therapeutics; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Depsipeptides; Small molecules
  • Mechanism of Action HDAC6 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Biliary cancer; Haematological malignancies; Solid tumours

Most Recent Events

  • 28 Sep 2022 Discontinued - Phase-I for Solid tumours (Late-stage disease, Monotherapy, Second-line therapy or greater) in USA (PO) (Karus Therapeutics website, September 2022).
  • 28 Sep 2022 Discontinued - Phase-II for Biliary cancer (Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in United Kingdom (PO) (Karus Therapeutics website, September 2022).
  • 28 Sep 2022 Discontinued - Preclinical for Haematological malignancies in USA (PO) (Karus Therapeutics website, September 2022).

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