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Pulocimab - AD Pharmaceuticals

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Drug Profile

Pulocimab - AD Pharmaceuticals

Alternative Names: AK-109

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator Akeso Biopharma
  • Developer AD Pharmaceuticals; Akeso Biopharma
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Angiogenesis inhibitors; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Gastric cancer
  • Phase II Liver cancer
  • Phase I/II Non-small cell lung cancer; Oesophageal cancer; Solid tumours

Most Recent Events

  • 28 Jan 2026 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Monotherapy, Recurrent, Refractory metastatic disease, Second-line therapy or greater, Treatment-resistant) in China (IV)
  • 09 Sep 2025 Safety and efficacy data from a phase Ib/II trial in Solid tumours presented at the 26th World Conference on Lung Cancer, 2025 (WCLC-2025)
  • 19 Jun 2024 Phase-III clinical trials in Gastric cancer (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV) (NCT06341335)

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