Drug Profile

Sunitinib maleate intravitreal - CalciMedica

Alternative Names: GB 102- CalciMedica; GB 103- CalciMedica; Intravitreal sunitinib maleate - CalciMedica

Latest Information Update: 22 Mar 2023

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At a glance

Originator GrayBug inc.
Developer CalciMedica
Class Amides; Antineoplastics; Ethylamines; Eye disorder therapies; Fluorobenzenes; Indoles; Pyrroles; Small molecules
Mechanism of Action Angiogenesis inhibitors; Colony-stimulating factor receptor antagonists; Fms-like tyrosine kinase 3 inhibitors; Platelet-derived growth factor alpha receptor antagonists; Platelet-derived growth factor beta receptor antagonists; Proto-oncogene protein c-kit inhibitors; Proto-oncogene protein c-ret inhibitors; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No
Available For Licensing Yes

Suspended Diabetic macular oedema; Retinal vein occlusion; Wet age-related macular degeneration
Discontinued Diabetic retinopathy

20 Mar 2023 GrayBug inc. has merged with CalciMedica to form CalciMedica
11 Aug 2022 Suspended - Phase-II for Diabetic macular oedema (Treatment-experienced) in USA due to cost-containment measures (Intravitreous)
11 Aug 2022 Suspended - Phase-II for Retinal vein occlusion (Treatment-experienced) in USA due to cost-containment measures (Intravitreous)

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