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Ecubectedin - PharmaMar

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Drug Profile

Ecubectedin - PharmaMar

Alternative Names: PM-14

Latest Information Update: 15 Sep 2025

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At a glance

  • Originator PharmaMar
  • Class Acetates; Antineoplastics; Aza compounds; Heterocyclic compounds with 4 or more rings; Indoles; Small molecules; Spiro compounds
  • Mechanism of Action RNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours
  • Phase I/II Soft tissue sarcoma
  • Phase I Prostate cancer

Most Recent Events

  • 19 Aug 2025 PharmaMar completes enrolment in its phase I trial for Solid tumours (Late-stage disease, Combination therapy, Second-line therapy or greater) in Spain (CTIS2023-509688-25-00) (EUCT2023-509688-25-00)
  • 25 Apr 2025 Pharmacodynamic data from a preclinical trial in Soft tissue sarcoma presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Solid tumors presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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