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Ecubectedin - PharmaMar

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Drug Profile

Ecubectedin - PharmaMar

Alternative Names: PM-14

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator PharmaMar
  • Class Acetates; Antineoplastics; Aza compounds; Heterocyclic compounds with 4 or more rings; Indoles; Small molecules; Spiro compounds
  • Mechanism of Action RNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours
  • Phase I/II Soft tissue sarcoma
  • Phase I Prostate cancer

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Solid tumors presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Solid tumors presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 13 Sep 2024 Efficacy, adverse events and pharmacokinetics data from a phase I/II trial in Solid tumours presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)

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