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Beremagene geperpavec - Krystal Biotech

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Drug Profile

Beremagene geperpavec - Krystal Biotech

Alternative Names: B-VEC; Bercolagene telserpavec; Beremagene geperpavec-svdt; HSV1-COL7; KB-103; KB-803; VYJUVEK

Latest Information Update: 18 Jun 2025

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At a glance

  • Originator Krystal Biotech
  • Class Gene therapies; Skin disorder therapies
  • Mechanism of Action COL7A1 protein replacements; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Epidermolysis bullosa dystrophica
  • New Molecular Entity No

Highest Development Phases

  • Marketed Epidermolysis bullosa dystrophica

Most Recent Events

  • 09 Jun 2025 Phase-III clinical trials in Epidermolysis bullosa dystrophica (In infants, In the elderly, In children, In adults, In adolescents) in USA (Ophthalmic) (NCT07016750)
  • 06 May 2025 Krystal Biotech expects a decision by Japan’s Pharmaceuticals and Medical Devices Agency (PMDA) on its Japan New Drug Application (JNDA) in second half of 2025
  • 06 May 2025 Krystal Biotech plans a phase III registrational IOLITE trial for Epidermolysis bullosa dystrophica, later this month

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