Autogene cevumeran - Genentech
Alternative Names: BNT-122; BNT122/RO7198457; Individualized Neoantigen Specific immunotherapy; iNeST; IVAC_M_uID; PCV RO7198457; Personalized cancer vaccine RO7198457; RG-6180; RG6180-1; RO-7198457Latest Information Update: 19 Feb 2025
Price :
$50 *
At a glance
- Originator BioNTech
- Developer BioNTech; Genentech; Memorial Sloan-Kettering Cancer Center; Roche
- Class Antineoplastics; Cancer vaccines; Immunotherapies; RNA vaccines
- Mechanism of Action Immunostimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase II Adenocarcinoma; Colorectal cancer; Malignant melanoma; Urogenital cancer
- Phase I Pancreatic cancer; Solid tumours; Triple negative breast cancer
Most Recent Events
- 21 Jan 2025 Genentech completes phase-II IMCODE001 clinical trials in Malignant melanoma (Combination therapy, First-line therapy, Late-stage disease, In the elderly, In adults) in Australia, US, Belgium, Germany, Spain and United Kingdom (IV) (NCT03815058) (EudraCT2018-001773-24)
- 05 Aug 2024 Immunogenicity data from a phase II trial in Colorectal cancer released by BioNTech
- 31 Jul 2024 Phase-II clinical trials in Urogenital cancer (Combination therapy, Adjuvant therapy) in Australia (IV) (NCT06534983)