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BNT 113

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Drug Profile

BNT 113

Alternative Names: BNT-113; E6/E7 RNA(LIP); HPV Anti-CD40 RNA Vaccine; HPV mRNA vaccine; RBLO 15.1(LIP)/RBLO 16.1(LIP)

Latest Information Update: 03 Feb 2026

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At a glance

  • Originator BioNTech
  • Developer BioNTech; University Hospital Southampton NHS Foundation Trust
  • Class Antineoplastics; Cancer vaccines; Immunotherapies; RNA vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II/III Squamous cell cancer
  • Phase I/II Cervical cancer; Penile cancer

Most Recent Events

  • 21 Jan 2026 BNT 113 receives Fast Track designation for Squamous cell cancer [IV,Injection] (Inoperable/Unresectable, Combination therapy, First-line therapy, Recurrent, Metastatic disease) in USA
  • 13 Sep 2024 Adverse events, immunogenicity and efficacy data from the phase I/II HARE-40 trial in Squamous cell cancer presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
  • 13 Sep 2024 Efficacy and adverse events data from the phase II AHEAD-MERIT trial in Squamous cell cancer presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)

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