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BNT 113

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Drug Profile

BNT 113

Alternative Names: BNT-113; E6/E7 RNA(LIP); HPV Anti-CD40 RNA Vaccine; HPV mRNA vaccine; RBLO 15.1(LIP)/RBLO 16.1(LIP)

Latest Information Update: 12 Feb 2024

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At a glance

  • Originator BioNTech
  • Developer BioNTech; University Hospital Southampton NHS Foundation Trust
  • Class Antineoplastics; Cancer vaccines; Immunotherapies; RNA vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Squamous cell cancer
  • Phase I/II Cervical cancer; Penile cancer

Most Recent Events

  • 24 Jan 2024 University of Southampton and Biontech completes the pgase I/II HARE-40 trial in Cervical cancer, Penile cancer and Squamous cell cancer (Second-line therapy or greater, Recurrent) in United Kingdom (Intradermal) (NCT03418480)
  • 03 May 2023 University of Southampton and Biontech temporarily suspend the first-in-human phase I/II HARE 40 trial for Squamous cell carcinoma, Cervical cancer and Penile cancer in United Kingdom (Intradermal), due to COVID-19 pandemic (NCT03418480) (EudraCT2014-002061-30)
  • 30 Mar 2021 BioNTech plans phase II trials for Squamous cell carcinoma (Combination therapy, First-line therapy) in USA and the European Union (IV) in first half of 2021

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