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Galegenimab - Genentech

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Drug Profile

Galegenimab - Genentech

Alternative Names: FHTR2163; RG-6147; RO-7171009

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Genentech
  • Class Eye disorder therapies; Immunoglobulin fragments; Monoclonal antibodies
  • Mechanism of Action High-temperature requirement A serine peptidase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Dry macular degeneration

Most Recent Events

  • 14 Nov 2022 Genentech terminates a phase II trial in Dry macular degeneration (In the elderly, In adults) in USA (Intravitreous) as the benefit to risk balance analysis did not support its further use (NCT04607148)
  • 27 Oct 2022 Genentech terminates a phase II trial in Dry macular degeneration (In the elderly, In adults) in USA (Intravitreous) as the benefit to risk balance analysis did not support its further use (NCT03972709)
  • 19 Oct 2022 Discontinued - Phase II trial for Dry macular degeneration (In adults, In the elderly) in USA (Intravitreal, Injection) (Roche pipeline, October 2022)

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