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Research programme: glycoimmune checkpoint inhibitors - Palleon Pharmaceuticals

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Drug Profile

Research programme: glycoimmune checkpoint inhibitors - Palleon Pharmaceuticals

Alternative Names: Anti-Siglec-9 antibodies - Palleon Pharmaceuticals; EAGLE-Her2; glycoimmune checkpoint inhibitors - Palleon Pharmaceuticals; Sialidase-PD-L1; Sialidase–Her2

Latest Information Update: 28 Apr 2025

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At a glance

  • Originator Howard Hughes Medical Institute; Stanford University; University of Dundee
  • Developer Palleon Pharmaceuticals
  • Class Anti-inflammatories; Antineoplastics; Enzymes; Monoclonal antibodies
  • Mechanism of Action Immunostimulants; Membrane glycoprotein modulators; Neuraminidase replacements; SIGLEC9 protein modulators; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer; Inflammation

Most Recent Events

  • 28 Apr 2025 No recent reports of development identified for preclinical development in Cancer in USA (Parenteral)
  • 28 Oct 2024 No recent reports of development identified for preclinical development in Inflammation in USA (Parenteral)
  • 14 Oct 2022 Palleon Pharmaceuticals has patent protection for use of antibody sialidase conjugates in USA

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