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Lutetium 177 vipivotide tetraxetan - Advanced Accelerator Applications

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Drug Profile

Lutetium 177 vipivotide tetraxetan - Advanced Accelerator Applications

Alternative Names: 177-Lutetium-PSMA-617 - Endocyte; 177Lu-EB-PSMA-617; 177Lu-PSMA; 177Lu-PSMA-617; 177LU-PSMA-617 - Endocyte; AAA617; Lu 177 vipivotide tetraxetan - Advanced Accelerator Applications; Lu177 RLT; Lutetium-177 PSMA 617; Pluvicto; Prvikt

Latest Information Update: 02 Mar 2026

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At a glance

  • Originator Endocyte; RadioMedix
  • Developer Advanced Accelerator Applications; Australian and New Zealand Urogenital and Prostate Cancer Group; Australian Nuclear Science and Technology Organisation; Novartis
  • Class Amides; Amines; Antineoplastics; Aza compounds; Carboxylic acids; Cyclic hydrocarbons; Cyclohexanes; Drug conjugates; Naphthalenes; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Prostate cancer

Most Recent Events

  • 02 Mar 2026 9461113: No updates (real-world effectiveness info of launched drug )
  • 01 Jan 2026 Novartis completes the phase II Bullseye trial in Prostate cancer (Metastatic disease) in Netherlands, Cyprus (IV)(NCT04443062)
  • 16 Dec 2025 Novartis initiates enrollment in a phase Ib/II trial in Prostate cancer (Hormone refractory, Combination therapy, Metastatic disease, Second-line therapy or greater) in Australia (IV) (NCT07226986)

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