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Sym 021

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Drug Profile

Sym 021

Alternative Names: Anti-PD-1 - Symphogen; S-95016; S095029 - Symphogen; Sym-021

Latest Information Update: 16 Dec 2024

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At a glance

  • Originator Symphogen
  • Class Antibodies; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • No development reported Lymphoma

Most Recent Events

  • 22 Nov 2024 Symphogen completes a phase-I clinical trial in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater) in Canada and the US (IV) (NCT04672434)
  • 24 Jun 2024 Sym 021 is still in Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, Combination therapy) in Canada (Parenteral) (NCT04672434)
  • 24 Jun 2024 Sym 021 is still in Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, Combination therapy) in USA (Parenteral) (NCT04672434)

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