Nitric oxide (SB 414)

Drug Profile

Nitric oxide (SB 414)

Alternative Names: SB414

Latest Information Update: 21 May 2018

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At a glance

  • Originator Novan Inc
  • Class Anti-inflammatories; Antiacnes; Antiandrogens; Antibacterials; Antifibrotics; Antifungals; Antihypertensives; Antipsoriatics; Antivirals; Free radicals; Macromolecular substances; Nitrogen oxides; Non-opioid analgesics; Small molecules; Vasodilators
  • Mechanism of Action Androgen receptor antagonists; Angiogenesis inducing agents; Cell death stimulants; Guanylate cyclase stimulants; Interleukin 13 inhibitors; Interleukin 4 inhibitors; Interleukin-17 inhibitors; Reactive oxygen species modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Atopic dermatitis; Psoriasis

Most Recent Events

  • 15 May 2018 Pharmacodynamics data from a preclinical trial in Atopic dermatitis released by Novan
  • 15 May 2018 Novan completes enrolment in a phase Ib trial for Atopic dermatitis in USA
  • 06 Feb 2018 Novan completes a phase I trial in Psoriasis in USA (Topical) (NCT03445013)
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