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Zevorcabtagene autoleucel - CARsgen

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Drug Profile

Zevorcabtagene autoleucel - CARsgen

Alternative Names: Anti-BCMA CAR T cell therapy - CARsgen; BCMA-redirected autologous T cells-CARsgen; CAR BCMA T-cell therapy-CARsgen; CAR-BCMA T Cell Infusion; CT-053 - CARsgen; Zevor-cel

Latest Information Update: 05 Nov 2024

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At a glance

  • Originator CARsgen
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity No

Highest Development Phases

  • Marketed Multiple myeloma

Most Recent Events

  • 05 Nov 2024 The US FDA liftes the clinical holds hold on clinical trials of zevorcabtagene autoleucel in USA
  • 13 Jun 2024 Adverse events and efficacy data from a phase I/II LUMMICAR-1 trial in Multiple Myeloma presented at the 29th Congress of the European Haematology Association (EHA-2024)
  • 15 Mar 2024 Launched for Multiple myeloma (Second-line therapy or greater) in China (IV) as of March 2024 - First Global Launch (CARsgen pipeline, March 2024)

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