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ATA 188

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Drug Profile

ATA 188

Alternative Names: Allogeneic ATA 188; Allogeneic EBV-directed T-cell therapy; ATA-188; EBV-CTLs; EBV-targeted T-cell; Epstein-Barr Virus-directed cytotoxic T lymphocytes; Off-the-shelf ATA188

Latest Information Update: 05 Apr 2024

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Developer Atara Biotherapeutics
  • Class Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - Multiple sclerosis

Highest Development Phases

  • Phase II Multiple sclerosis

Most Recent Events

  • 04 Apr 2024 ATA 188 is available for licensing as of 05 Apr 2024. https://www.sec.gov/ix?doc=/Archives/edgar/data/1604464/000095017024037644/atra-20231231.htm
  • 04 Apr 2024 Atara Biotherapeutics paused the development for Multiple sclerosis (Atara Biotherapeutics SEC 2024)
  • 17 Jan 2024 Atara Biotherapeutics terminates a phase I/II EMBOLD trial in Multiple sclerosis (Treatment-experienced) in USA, Australia, and Canada (IV), due to the primary endpoint not being achieved (NCT03283826)

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