Allogeneic ATA 188

Drug Profile

Allogeneic ATA 188

Alternative Names: Allogeneic EBV-directed T-cell therapy; ATA188; EBV-CTLs; EBV-targeted T-cell; Epstein-Barr Virus-directed cytotoxic T lymphocytes; Off-the-shelf ATA188

Latest Information Update: 26 Mar 2018

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Developer Atara Biotherapeutics
  • Class Gene therapies; Immunotherapies; Neuroprotectants; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Multiple sclerosis
  • Preclinical Solid tumours

Most Recent Events

  • 22 Mar 2018 Phase-I clinical trials in Multiple sclerosis (Treatment-experienced) in USA (IV) (NCT03283826)
  • 10 Jan 2018 US FDA approves IND application for ATA 188 in Multiple sclerosis
  • 27 Oct 2017 Preclinical trials in Solid tumours in USA (unspecified route) (Atara Biotherapeutics pipeline, October 2017)
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