Research programme: c-Abl inhibitors - 1ST Bio/Neuraly

Drug Profile

Research programme: c-Abl inhibitors - 1ST Bio/Neuraly

Alternative Names: 1ST-102; Parkinson's disease therapeutics

Latest Information Update: 31 Oct 2017

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At a glance

  • Originator 1St Biotherapeutics
  • Developer 1St Biotherapeutics; Neuraly
  • Class Neuroprotectants; Small molecules
  • Mechanism of Action Bcr-abl tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Parkinson's disease

Most Recent Events

  • 25 Oct 2017 1ST Bio and Neuraly agree to co-develop c-Abl inhibitors in South Korea for Parkinson's disease
  • 25 Oct 2017 Preclinical trials in Parkinson's disease in South Korea (unspecified route)
  • 25 Oct 2017 1ST BIO intends to file an IND application for Parkinson's disease in 2018
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