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Tarlatamab - Amgen

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Drug Profile

Tarlatamab - Amgen

Alternative Names: AMG-757; IMDELLTRA; Imdelltra; IMDYLLTRA; Tarlatamab-dlle

Latest Information Update: 28 Feb 2026

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At a glance

  • Originator Amgen
  • Developer Amgen; BeOne Medicines
  • Class Antineoplastics; Bispecific antibodies; Immunoglobulin Fc fragments; Immunoglobulin fragments; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Small cell lung cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Small cell lung cancer
  • Phase I/II Glioma
  • Discontinued Malignant melanoma; Prostate cancer

Most Recent Events

  • 28 Feb 2026 No recent reports of development identified for phase-I development in Small-cell-lung-cancer(Combination therapy) in Austria (IV, Infusion)
  • 28 Feb 2026 No recent reports of development identified for phase-I development in Small-cell-lung-cancer(Combination therapy) in Belgium (IV, Infusion)
  • 28 Feb 2026 No recent reports of development identified for phase-I development in Small-cell-lung-cancer(Combination therapy) in Japan (IV, Infusion)

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