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Tarlatamab - Amgen

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Drug Profile

Tarlatamab - Amgen

Alternative Names: AMG-757; IMDELLTRA; Imdelltra; IMDYLLTRA; Tarlatamab-dlle

Latest Information Update: 11 Jun 2025

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At a glance

  • Originator Amgen
  • Class Antineoplastics; Bispecific antibodies; Immunoglobulin Fc fragments; Immunoglobulin fragments; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Small cell lung cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Small cell lung cancer
  • Phase I Prostate cancer
  • Discontinued Malignant melanoma

Most Recent Events

  • 02 Jun 2025 Efficacy and safety data from the phase III DeLLphi-304 trial in Small cell lung cancer released by Amgen
  • 30 May 2025 Phase-I clinical trials in Small cell lung cancer (Combination therapy, Second-line therapy or greater) in China, USA (IV) (NCT06898957)
  • 11 Apr 2025 Efficacy and safety data from the phase III DeLLphi-304 trial in Small cell lung cancer released by Amgen

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