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Danavorexton - Takeda

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Drug Profile

Danavorexton - Takeda

Alternative Names: TAK-925

Latest Information Update: 07 Jul 2025

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At a glance

  • Originator Takeda
  • Class Cyclohexanes; Esters; Ethers; Piperidines; Sleep disorder therapies; Small molecules; Sulfonamides
  • Mechanism of Action Orexin receptor type 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Narcolepsy
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Idiopathic hypersomnia; Narcolepsy; Neurological disorders; Respiration disorders; Sleep apnoea syndrome

Most Recent Events

  • 07 Jul 2025 Discontinued - Phase-I for Idiopathic hypersomnia (In the elderly, In adults) in USA, Japan (IV) (Takeda pipeline, July 2025)
  • 07 Jul 2025 Discontinued - Phase-I for Narcolepsy (In the elderly, In adults) in Japan (IV) (Takeda pipeline, July 2025)
  • 07 Jul 2025 Discontinued - Phase-I for Narcolepsy (In volunteers) in USA (IV) (Takeda pipeline, July 2025)

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