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MTV 273

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Drug Profile

MTV 273

Alternative Names: CART BCMA; CART-BCMA - Novartis; MTV-273

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator University of Pennsylvania
  • Developer Novartis; University of Pennsylvania
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Multiple myeloma

Most Recent Events

  • 27 Jul 2020 University of Pennsylvania completes a phase I trial in Multiple myeloma (Second-line therapy or greater) in USA (IV) (NCT02546167)
  • 07 Dec 2019 Updated efficacy and adverse events data from a phase I Multiple myeloma presented at the 61st Annual Meeting and Exposition of the American Society of Hematology (ASH-Hem-2019)
  • 19 Mar 2019 Discontinued - Phase-I for Multiple myeloma (Combination therapy) in USA (IV)

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