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Research programme: uPARAP targeting antibody drug conjugates - ADCendo/University of Copenhagen

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Drug Profile

Research programme: uPARAP targeting antibody drug conjugates - ADCendo/University of Copenhagen

Alternative Names: ADC targeting the uPARAP receptor; Monomethyl auristatin E-conjugated antibody - University of Copenhagen/ADCendo; uPARAP/Endo180 programme

Latest Information Update: 29 Nov 2024

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At a glance

  • Originator Rigshospitalet; University of Copenhagen
  • Developer ADCendo; Rigshospitalet; University of Copenhagen
  • Class Antibodies; Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 25 Nov 2024 Adcendo exercises its option to utilize Duality Biologics' platform to further enhance its first-in-class ADC pipeline
  • 29 May 2024 Preclinical trials in Cancer is ongoing in Denmark (Parenteral)
  • 28 Jul 2023 No recent reports of development identified for preclinical development in Cancer in Denmark (Parenteral)

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