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Suvodirsen - Wave Life Sciences

Drug Profile

Suvodirsen - Wave Life Sciences

Alternative Names: BMTR-0139; Exon 51 modulators - Wave Life Sciences; Suvodirsen sodium; Suvodirsen sodium - Wave Life Sciences; WLS-4176; WV-3473; WVE-210201

Latest Information Update: 24 Dec 2019

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At a glance

  • Originator WaVe life Sciences
  • Class Antisense oligonucleotides
  • Mechanism of Action Dystrophin expression modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Duchenne muscular dystrophy

Most Recent Events

  • 19 Dec 2019 Wave Life Sciences terminates the phase I OLE trial in Duchenne muscular dystrophy in US, Belgium, Canada, France, Italy, the Netherlands and the United Kingdom (NCT03508947)
  • 19 Dec 2019 Wave Life Sciences terminates the phase II/III DYSTANCE 51 trial in Duchenne muscular dystrophy in US, Canada, Italy and Sweden (NCT03907072)
  • 17 Dec 2019 Discontinued - Phase-I for Duchenne muscular dystrophy (In adolescents, In children) in United Kingdom (IV), Netherlands (IV), Belgium (IV), Canada (IV), Italy (IV), France (IV)
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