Zigakibart - Chinook Therapeutics
Alternative Names: Anti-APRIL monoclonal antibody - Chinook Therapeutics; BION-1301; FUB 523; FUB-523 - NovartisLatest Information Update: 06 Feb 2024
At a glance
- Originator Aduro BioTech
- Developer Aduro BioTech; Chinook Therapeutics
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants; Tumour necrosis factor ligand superfamily member 13 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III IgA nephropathy
- Discontinued Multiple myeloma
Most Recent Events
- 06 Feb 2024 Novartis plans to file a regulatory submissions for zigakibart for IgA nephropathy in or after 2027 (Novartis pipeline, February 2024)
- 05 Jan 2024 SanReno Therapeutics has been acquired by Novartis
- 11 Aug 2023 Chinook Therapeutics has been acquired by Novartis