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PXS 5382A

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Drug Profile

PXS 5382A

Alternative Names: PXS-5382; PXS-5382A

Latest Information Update: 13 Dec 2023

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At a glance

  • Originator Pharmaxis
  • Developer Synairgen; Syntara Limited
  • Class Antifibrotics; Antineoplastics; Hepatoprotectants; Pyrans; Small molecules
  • Mechanism of Action LOXL2 protein inhibitors; Protein lysine 6 oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Idiopathic pulmonary fibrosis; Non-alcoholic steatohepatitis

Highest Development Phases

  • Preclinical Renal failure
  • No development reported Idiopathic pulmonary fibrosis; Non-alcoholic steatohepatitis
  • Discontinued Cancer; Renal fibrosis

Most Recent Events

  • 04 Dec 2023 Pharmaxis is now called Syntara Limited
  • 28 May 2023 No recent reports of development identified for phase-I development in Idiopathic-pulmonary-fibrosis(In volunteers) in Australia (PO, Tablet)
  • 28 May 2023 No recent reports of development identified for phase-I development in Non-alcoholic-steatohepatitis(In volunteers) in Australia (PO)

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