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PGT 121

Drug Profile

PGT 121

Alternative Names: PGT121

Latest Information Update: 24 Apr 2024

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At a glance

  • Originator Theraclone Sciences
  • Developer Centre for the AIDS Programme of Research in South Africa; International AIDS Vaccine Initiative; The Ragon Institute of MGH, MIT and Harvard
  • Class Antivirals; Cancer vaccines; Monoclonal antibodies
  • Mechanism of Action HIV envelope protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • No development reported HIV infections

Most Recent Events

  • 03 Mar 2024 Efficacy data from a phase I/IIa trial in HIV infections presented at the 31st Conference on Retroviruses and Opportunistic Infections 2024 Session (CROI-2024)
  • 02 May 2022 International AIDS Vaccine Initiative completes a phase I/IIa trial in HIV infections (Combination therapy) in USA (IV) (NCT03721510)
  • 12 Feb 2022 Pharmacodynamics data from preclinical trials in HIV infection presented at the 29th Conference on Retroviruses and Opportunistic Infections (CROI-2022)
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