Drug Profile


Alternative Names: DCR-PHXC

Latest Information Update: 11 Dec 2017

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At a glance

  • Originator Dicerna Pharmaceuticals
  • Class Small interfering RNA
  • Mechanism of Action Oxalate modulators; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Primary hyperoxaluria

Most Recent Events

  • 08 Mar 2018 Dicerna plans to submit CTAs for the PHYOX study in other European countries in 2019
  • 08 Mar 2018 Dicerna plans a multi-dose phase II/III trial for Primary hyperoxaluria in first quarter of 2019
  • 07 Dec 2017 Phase-I clinical trials in Primary hyperoxaluria in United Kingdom (SC)
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