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Drug Profile

Psilocybin - COMPASS Pathways

Alternative Names: COMP-360; Psilocybine

Latest Information Update: 09 Apr 2025

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At a glance

  • Originator COMPASS Pathways
  • Developer COMPASS Pathways; Imperial College of Science, Technology and Medicine; Johns Hopkins University
  • Class Analgesics; Anti-infectives; Anti-inflammatories; Antidepressants; Antineoplastics; Antipsychotics; Anxiolytics; Behavioural disorder therapies; Dimethylamines; Drug withdrawal therapies; Indoles; Mood stabilisers; Neuropsychotherapeutics; Organophosphorus compounds; Phytotherapies; Small molecules
  • Mechanism of Action ATP-binding cassette transporter modulators; Serotonin 5-HT2 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Depressive disorders
  • Phase II Anorexia nervosa; Bipolar depression; Major depressive disorder; Post-traumatic stress disorders; Somatoform disorders
  • Phase Unknown Pervasive child development disorders

Most Recent Events

  • 26 Mar 2025 Compass Pathways completes enrolment of patients in phase-III COMP005 trials in Depressive disorders (Treatment-resistant) in United Kingdom (PO) (NCT05624268)
  • 18 Mar 2025 Adverse events and efficacy data from a phase II trial in Depressive disorders released by Compass Pathways
  • 26 Feb 2025 COMPASS Pathways plans a late-stage clinical trial for Post-traumatic stress disorders

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