Psilocybin - COMPASS Pathways
Alternative Names: COMP-360; PsilocybineLatest Information Update: 20 Jan 2026
At a glance
- Originator COMPASS Pathways
- Developer COMPASS Pathways; Imperial College of Science, Technology and Medicine; Johns Hopkins University
- Class Analgesics; Anti-infectives; Anti-inflammatories; Antidepressants; Antineoplastics; Antipsychotics; Anxiolytics; Behavioural disorder therapies; Dimethylamines; Drug withdrawal therapies; Ethylamines; Indoles; Mood stabilisers; Neuropsychotherapeutics; Organophosphorus compounds; Phosphates; Phytotherapies; Small molecules
- Mechanism of Action ATP-binding cassette transporter modulators; Serotonin 5-HT2 receptor agonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase III Treatment-resistant depressive disorder
- Phase II Anorexia nervosa; Bipolar depression; Major depressive disorder; Post-traumatic stress disorders; Somatoform disorders
- Clinical Phase Unknown Autism spectrum disorder
Most Recent Events
- 07 Jan 2026 the US FDA accepts its Investigational New Drug (IND) application for phase IIb/III COMP202 clinical trial in patients with Post-traumatic stress disorders (PTSD)
- 07 Jan 2026 Compass Pathways plans phase IIb/III COMP202 clinical trial in patients with Post-traumatic stress disorders (PTSD)
- 13 Nov 2025 VA Office of Research and Development plans a phase III PIVOT trial for Major depressive disorder in USA in June 2026 (NCT07226232)