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MEDI 2228

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Drug Profile

MEDI 2228

Alternative Names: MEDI2228

Latest Information Update: 05 Apr 2022

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At a glance

  • Originator MedImmune
  • Class Antineoplastics; Benzodiazepines; Drug conjugates; Immunoconjugates; Monoclonal antibodies; Pyrroles
  • Mechanism of Action Cell death stimulants; DNA cross linking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Multiple myeloma

Most Recent Events

  • 05 Apr 2022 Medimmune completes phase I trial in Multiple myeloma (Second-line therapy or greater) in USA, Australia, Greece (Parenteral) in March 2022 (NCT03489525)
  • 01 Apr 2021 Discontinued - Phase-I for Multiple myeloma (In the elderly, Second-line therapy or greater, In adults) in Australia, Greece (Parenteral) (AstraZeneca pipeline, April 2021)
  • 01 Apr 2021 Discontinued - Phase-I for Multiple myeloma (In the elderly, Second-line therapy or greater, In adults) in USA (Parenteral) due to safety/efficacy reasons by AstraZeneca (AstraZeneca pipeline, April 2021)

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